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“Every pregnancy is at risk of having pregnancy complications,” explains @DrSteveRad, a board-certified OB-GYN and maternal-fetal medicine specialist. “So a lot of us—especially high-risk doctors—have changed the name to ‘at-risk pregnancies.’” What makes a pregnancy high-risk? Lifestyle factors play a major role. At age 25, the chance of having a baby with Down Syndrome is about 1 in 1,250. By age 40, it rises to 1 in 100. Preeclampsia rates also climb: 30% higher for women 40 to 44 compared to those 35 to 39, and more than double for women over 45.